ELOCALCITOL

ELOCALCITOL

Stock Code: 3576255
Manufacturer Part No: SML2395-1MG
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£167.84 (exc VAT) per 1MG
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Biochem/physiol Actions


Elocalcitol is a Vitamin D receptor (VDR) agonist and is an analog of calcitriol. Elocalcitol possesses anti-inflammatory and anti- proliferative properties. It regulates cell apoptosis and cell proliferation by binding to Vitamin D receptors (VDR). It shows a therapeutic effect on people suffering from Benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS).


Elocalcitol (BX-L628) is an analog of Vitamin D3 that acts as an agonist at vitamin D VDR receptors. It has been shown to inhibit prostate cell growth and RhoA/Rho-kinase signaling. Elocalcitol (BXL-628) downregulated the expression of active RhoA and ROCK activity induced by high glucose and was shown to have renal protective effects.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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