DL-beta-Hydroxybutyric acid sodium salt, approx.98%

Stock Code: 3578337
Manufacturer Part No: H6501-5G

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Descriptions

Application

DL-?-Hydroxybutyric acid sodium salt has been used:as a standard for quantifying blood plasma and milk ?-hydroxybutyric acid in Danish Jersey cowsto investigate its anticonvulsant effects in epilepsy induced ratsto induce hyperketonemia in Holstein dairy cows

Biochem/physiol Actions

?-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD⁺, measured fluorimetrically. A high plasma level of ?-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. ?-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson?s disease model. ?-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).

Packaging

5, 25, 100 g in poly bottle

Specifications

Quality Level	200
InChI key	NBPUSGBJDWCHKC-UHFFFAOYSA-M
InChI	1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
Manufacturer	SIGMA-ALDRICH
Storage Temp.	2-8°C
Solubility	water: 1 g/10 mL, clear, colorless
Form	powder
Assay	~98%