DIASARONE-I

DIASARONE-I

Stock Code: 3576166
Manufacturer Part No: SML2337-5MG
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£111.29 (exc VAT) per 5MG
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Biochem/physiol Actions


Diasarone-I is an antiviral agent isolated form Acorus tatarinowii Schott that potently inhibits dengue viral infection. Diasarone-I is binds to the viral 2′O methyltransferase of nonstructural protein 5 (NS5). It also decreases the DENV2-induced STAT1 phosphorylation and IFN-stimulated genes (ISGs) expression.


The antiviral effect of Diasarone-I includes half maximal effective concentration (EC50) of 4.5 ?M and half maximal cytotoxicity concentration (CC50) of >80 ?M.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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