CRANAD 2

CRANAD 2

Stock Code: 3574159
Manufacturer Part No: SML0842-25MG
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£552.96 (exc VAT) per 25MG
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Biochem/physiol Actions


CRANAD 2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM. Upon interacting with Aβ aggregates, CRANAD 2 exhibits a 70-fold increase in fluorescence intensity accompanied by a 90 nm blue shift from 805 to 715 nm and a large increase in quantum yield. CRANAD 2 has been used to detect Aβ deposits noninvasively in vivo in transgenic Tg2576 mice.


Packaging


5, 25 mg in glass bottle

Colour, dark blue to black
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 0.2 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

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