CID16020046 has been used as an antagonist of G-protein coupled receptor(GPR55) to test its effect on nociceptive behavior in rats induced with formalin.
Biochem/physiol Actions
CID16020046 is a potent and a selective GPR55 antagonist that inhibits GPR55-mediated ERK1/2 phosphorylation. CID16020046 inhibits LPI-induced Ca2+ signaling in HEK-GPR55 cells.