CCG-63802,

Stock Code: 3573981
Manufacturer Part No: SML0016-5MG
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£113.10 (exc VAT) per 5MG
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Application


CCG-63802 may be used to study G-protein-mediated cell signaling.


Biochem/physiol Actions


GCC-63802 binds to RGS4 and blocks interaction with Goa (IC50 = 1.9 uM). RGS4 (Regulator of G protein Signaling) is one of the RGP proteins responsible for terminating mu opioid receptor signaling. RSG proteins are GTPase activators, and drive G protein subunits to an inactive, GDP-bound form.


Features and Benefits


This compound is featured on the G Proteins (Heterotrimeric) and Opioid Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


Packaging


5, 25 mg in glass bottle

Colouryellow
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.room temp
SolubilityDMSO: ≥5 mg/mL (;warmed DMSO)
Formpowder
Assay≥98% (HPLC)

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