BETA-ODAP

BETA-ODAP

Stock Code: 3575441
Manufacturer Part No: SML1836-25MG
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£668.57 (exc VAT) per 25MG
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Biochem/physiol Actions


β-ODAP is a potent inhibitor of HIF-prolyl hydroxylase-2 (PHD-2) that induces HIF dependent HRE (hypoxia response element) in normoxic conditions. β-ODAP is an analog of glutamic acid present in Lathyrus sativus (grass pea) that activates AMPA receptors. β-ODAP causes neurolathyrism upon prolonged consumption of L. sativus seeds.


?-ODAP is considered more neurotoxic than ?-ODAP, thus during food processing, its conversion to ? isomer is essential. ?-ODAP exhibits its neurotoxicity via the activation of metabotropic glutamatergic receptor.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyNEEQFPMRODQIKX-REOHCLBHSA-N
InChI1S/C5H8N2O5/c6-2(4(9)10)1-7-3(8)5(11)12/h2H,1,6H2,(H,7,8)(H,9,10)(H,11,12)/t2-/m0/s1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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