BAY-6035

BAY-6035

Stock Code: 3576148
Manufacturer Part No: SML2325-5MG
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£156.00 (exc VAT) per 5MG
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Biochem/physiol Actions


BAY-6035 is a substrate-competitive, potent and selective SMYD3 inhibitor (IC50 = 88 nM by cell-free MEKK2 peptide methylation; IC50 = 70 nM against cellular MEKK2 methylation) with >100-fold selectivity over other histone methyltransferases. BAY-211 is a structural analog and the recommended inactive control (IC50 = 23 µM by cell-free MEKK2 peptide methylation) for BAY-6035. For characterization details of BAY-6035, please visit the BAY-6035 probe summary on the Structural Genomics Consortium (SGC) website.BAY-444 is the negative control for the active probe, BAY-6035. To request a sample of the negative control from the SGC, click here.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc


Features and Benefits


BAY-6035 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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