AZORAMIDE

AZORAMIDE

Stock Code: 3575088
Manufacturer Part No: SML1560-10MG
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£122.85 (exc VAT) per 10MG
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Biochem/physiol Actions


Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It has dual activity: Azoramide improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones that protect cells against ER stress. Azoramide was shown to protect cells from death and dysfunction in multiple models of ER stress. It showed antidiabetic activity in two independent mouse models of obesity by improving insulin sensitivity and protecting pancreatic β cell function against ER stress.


Packaging


10, 50 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyVYBFWKKCWTXCQX-UHFFFAOYSA-N
InChI1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 30 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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