Atropine sulfate salt hydrate has been used:to assay specific binding of high-affinity 3-quinuclidinyl benzilate-3H ([3H]QNB) to the muscarinic acetylcholine receptor (mAChR)to block the recovery phase of the aldicarb (Ald) responseas an analyte for liquid chromatography with tandem mass spectrometry (LC-MS/MS)as a mAChR antagonist to block acetylcholine receptor
Biochem/physiol Actions
Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.
General description
Atropine is isolated from Atropa belladonna, Datura stramonium and Mandragora officinarum. It is a tertiary amine, which acts as a cholinergic receptor antagonist.