ATN-161

ATN-161

Stock Code: 3575791
Manufacturer Part No: SML2079-25MG
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£718.71 (exc VAT) per 25MG
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Application


ATN-161 has been used as an inhibitor of integrin ?5?1 and ?v?3 in cultured platelet endothelial cell adhesion molecule (PECAM1)-positive endothelial cells isolated from AL (CECAL).


Biochem/physiol Actions


ATN-161 is a non-RGD based integrin binding peptide derived from the synergy region of fibronectin that inhibits the receptors for integrins alpha-v beta-3 and integrin alpha-5 beta-1. Integrin alpha-5 beta-1 is expressed on endothelial cells and plays a key role in endothelial cell adhesion and migration and may also play a key role in cancer cell invasion and metastasis. ATN-161 was shown to have antiangigenic and antitumor activity.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formpowder
Assay≥98% (HPLC)

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