APRATASTAT

APRATASTAT

Stock Code: 3575058
Manufacturer Part No: SML1543-25MG
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£754.93 (exc VAT) per 25MG
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Biochem/physiol Actions


Apratastat (TMI-005) is an orally active, potent and selective dual inhibitor of disintegrin metalloenzyme 17 (ADAM17/ TACE) and matrix metalloprotease (MMP).


General description


Apratastat is one of the thiomorpholine sulfonamide hydroxymate selective inhibitors of ADAM17 (a disintegrin and metalloproteinase).


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyMAVDNGWEBZTACC-HNNXBMFYSA-N
InChI1S/C17H22N2O6S2/c1-17(2)15(16(21)18-22)19(9-12-26-17)27(23,24)14-7-5-13(6-8-14)25-11-4-3-10-20/h5-8,15,20,22H,9-12H2,1-2H3,(H,18,21)/t15-/m0/s1
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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