AMBRISENTAN

AMBRISENTAN

Stock Code: 3575826
Manufacturer Part No: SML2104-10MG
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£178.29 (exc VAT) per 10MG
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Biochem/physiol Actions


Ambrisentan is an endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH). It is 200-fold selective for the the ETA receptor subtype with a Ki of 1 nM for ETA and a Ki of 195 nM for ETB.

Colourwhite to beige
InChI keyOUJTZYPIHDYQMC-UHFFFAOYSA-N
InChI1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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