Albumin from human serum, lyophilized powder, >=97% (agarose gel electrophoresis)

Albumin from human serum, lyophilized powder, >=97% (agarose gel electrophoresis)

Stock Code: 3589666
Manufacturer Part No: A9511-5G
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£1,145.43 (exc VAT) per 5G
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Application

Albumin-bound fluorescence was used in serum of patients with chronic renal failure.

Albumin from human serum has been used:to standardize the column for molecular-exclusion chromatographyto prepare the tobacco mosaic virus (TMV)-poly ethylene glycol (PEG8)-serum albumin (SA) particlesto analyze its modifications after oxidation using a Fenton system

Biochem/physiol Actions

Albumin turnover is seen in infants with iron deficiency anemia. Serum albumin is a reliable prognostic indicator in liver disease. Oxidative modification of albumin is seen in advanced liver disease.

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.

General description

Albumin is the most copious protein in blood plasma. Liver produces human albumin.

Human albumin possess a molecular weight of 67 kDa.

Other Notes

View more information on human serum albumin.

Packaging

100, 500 mg in poly bottle

1, 5, 10, 25 g in poly bottle

Preparation Note

Prepared using method IV of Cohn, E.J., et al., J. Am. Chem. Soc., 69, 1753 (1947).

Quality Level300
ManufacturerSIGMA-ALDRICH
ImpuritiesHIV I and HIVII, HCV and HBsAg, tested negative
SolubilityH2O: soluble 50 mg/mL
Formlyophilized powder
Assay≥97% (agarose gel electrophoresis)

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