ACT-462206

ACT-462206

Stock Code: 3574851
Manufacturer Part No: SML1393-5MG
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£99.03 (exc VAT) per 5MG
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Biochem/physiol Actions


ACT-462206 is a orally active, brain penetrant, potent and selective dual orexin1/2 receptor antagonist (DORA). ACT-462206 decreases wakefulness, decreases sleep latency, and increases sleep efficacy in rats and dogs.


ACT-462206 is a proline sulphonamide with the potential to treat insomnia. On absorption, its displays asthenia, blurred vision, and fatigue as adverse events.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyNHPQGZOBHSVTAQ-IBGZPJMESA-N
InChI1S/C20H24N2O4S/c1-14-11-15(2)13-16(12-14)21-20(23)19-5-4-10-22(19)27(24,25)18-8-6-17(26-3)7-9-18/h6-9,11-13,19H,4-5,10H2,1-3H3,(H,21,23)/t19-/m0/s1
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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