14-3-3 zeta, untagged human, recombinant, expressed in E. coli, >=70% (SDS-PAGE), buffered aqueous g

14-3-3 zeta, untagged human, recombinant, expressed in E. coli, >=70% (SDS-PAGE), buffered aqueous g

Stock Code: 3593407
Manufacturer Part No: SRP5156-50UG
Order Now for 7 day delivery
£300.86 (exc VAT) per 50UG
Quantity: - +

General description

14-3-3ζ (also known as tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide) is a member of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3ζ protein plays a key role in cancer biology by being an important regulator of major cellular processes such as proliferation, differentiation, senescence and apoptosis. 14-3-3ζ protein has been shown to interact with the IRS1 protein, suggesting a role for this protein in regulating insulin sensitivity by interrupting the association between the insulin receptor and IRS1.

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

ManufacturerSIGMA-ALDRICH
Formbuffered aqueous glycerol solution
Assay≥70% (SDS-PAGE)

There are no downloads for this product.