Ubiquitin-Specific Protease 14 human, recombinant, expressed in Sf9 cells, >=75% (SDS-PAGE)

Ubiquitin-Specific Protease 14 human, recombinant, expressed in Sf9 cells, >=75% (SDS-PAGE)

Stock Code: 3581515
Manufacturer Part No: U6385-50UG
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£883.74 (exc VAT) per 50UG
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Application


Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.


General description


Human USP14 (Ubiquitin-Specific Protease 14) or TGT (tRNA-guanine transglycosylase), amino acids 2-494 (end) with an N-terminal FLAG-tag, expressed in a baculovirus-infected Sf9 cell expression system. Ubiquitin-Specific Protease 14 is a deubiquitinating protein responsible for the removal of ubquitin tags attached to proteins by ?NH-peptide bonds and the ?-NH-isopeptide bond.


USP14 has been shown to be phosphorylated by AKT which is required for protein stability and nuclear localization.


Physical form


Solution in 40 mM Tris-HCl, 110 mM NaCl, 2.2 mM KCl, 80 ng/µl Flag peptide, 3 mM DTT, and 20% Glycerol at pH 8.0.

Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.−70°C
Formbuffered aqueous glycerol solution
Assay≥75% (SDS-PAGE)

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