Human S100B ELISA - 96-Well Plate Assay

Human S100B ELISA - 96-Well Plate Assay

Stock Code: 3577539
Manufacturer Part No: EZHS100B-33K
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Application


Research CategoryNeuroscience


This is a same day assay


Used to detect/quantify: S100B


Disclaimer


For research use only. Not for use in diagnostic procedures.


General description


S100B is a calcium-binding protein produced mainly by astrocytes in the central nervous system and has been implicated in the development and maintenance of the nervous system. Although the mechanism of S100B secretion is unknown, it appears to be affected by oxidative stress. At nanomolar concentrations (normal levels), S100B is able to protect neurons against glutamate toxicity. Glial damage or astrocytic reactions to neural injury (reactive astrogliosis) causes an increase in S100B to micromolar concentrations. High levels of S100B will further increase neuronal damage. High levels of S100B are considered a biomarker that could indicate damage or dysfunction of CNS.


EMD Millipore's Human S100B ELISA kit is to be used for the quantification of human S100B in cerebrospinal fluid, serum and plasma. This kit has not been tested for cell culture supernatants.


Other Notes


Please contact Technical Service for linearity of dilution.


Specificity


The antibody pair used in this assay measures Human S100B and has no cross-reactivity with S100A1, S100A6 and S100A13.

This assay detects S100B in multiple species, including: bovine, hamster, horse, monkey, mouse, pig, rabbit, and rat.

Quality Level100
ManufacturerSIGMA-ALDRICH
Technique(s)ELISA: suitable

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