(Z-LL)2 KETONE

(Z-LL)2 KETONE

Stock Code: 3574912
Manufacturer Part No: SML1442-1MG
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£84.41 (exc VAT) per 1MG
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Biochem/physiol Actions


(Z-LL)2 Ketone is a selective inhibitor of signal peptide peptidase (SPP) that inhibits processing of the p-Prl signal peptide (IC50 = ~ 50 nM) without affecting the activities of signal peptidases and other proteases such as lysosomal cathepsins and proteasomes.


(Z-LL)2 Ketone serves as an inverse ?-secretase modulator (iGSM) by changing processivity of ?-secretase cleavage.


Packaging


1 mg in glass bottle

Colourwhite to light yellow
Quality Level100
InChI keyJTVCWQUNPMKMER-BQYLNSIHSA-N
InChI1S/C43H64N6O9/c1-27(2)19-34(46-40(53)36(21-29(5)6)48-42(55)57-25-31-15-11-9-12-16-31)38(51)44-23-33(50)24-45-39(52)35(20-28(3)4)47-41(54)37(22-30(7)8)49-43(56)
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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