STRO-1; MSX; 100UL

Stock Code: 3572019
Manufacturer Part No: MAB4315
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Analysis Note


ControlBone marrow cultures


Application


Detect STRO-1 using this Anti-STRO-1 Antibody, clone STRO-1 validated for use in FC & IF.


General description


STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells. The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes.


Immunogen


CD34+ bone marrow cells


Legal Information


CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


Specificity


Recognizes a cell surface antigen expressed by bone marrow stromal cells and stromal precursors. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors.

Quality Level100
ManufacturerSIGMA-ALDRICH

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