SDF-1ALPHA(CXCL12)HUMANRECOMBINANTANIMA

SDF-1ALPHA(CXCL12)HUMANRECOMBINANTANIMA

Stock Code: 3571831
Manufacturer Part No: GF344
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Application


Research CategoryStem Cell Research


Research Sub CategoryGrowth Factors & Receptors


Disclaimer


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


General description


Product Source: Protein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.


SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.
Recombinant human SDF-1α is an 8.0 kDa protein containing 68 amino acid residues.


Physical form


Product is presented without additives and is filtered through a 0.2 micron filter before lyophilization.


Quality


Determined by its ability to chemoattract IL-2-activated human T cells using a concentration range of 20.0- 80.0 ng/ml.


Storage and Stability


Store at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.

Quality Level100
ManufacturerSIGMA-ALDRICH
Impurities﹤0.1 µg/mg protein endotoxin (<1 EU/µg)

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