Recombinant Human Endostatin; 100ug

Stock Code: 3571781
Manufacturer Part No: GF171
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£431.79 (exc VAT) per EACH
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Application


Research CategoryStem Cell Research


Research Sub CategoryGrowth Factors & Receptors


Disclaimer


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


General description


Product Source: E. coli.


Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.


Physical form


Product is filtered through a 0.2 micron filter before lyophilization.


Quality


Bioactivity assay: Measured by its ability to inhibit HUVEC migration.


Specificity


Cross ReactivtyNone


Storage and Stability


Store at -20°C for up to 6 months from date of receipt.

Quality Level100
ManufacturerSIGMA-ALDRICH
Impurities﹤0.1 µg/mg protein endotoxin (<1EU/µg)
Assay>98% (SDS-PAGE and HPLC)

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