MILLI-MARK ANTI-SSEA-1;CLONE MC-48

Stock Code: 3571693
Manufacturer Part No: FCMAB117P
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Analysis Note


ControlMouse embryonic Stem Cells


Application


Research CategoryStem Cell Research


Research Sub CategoryPluripotent & Early Differentiation


Anti-SSEA-1 Antibody, clone MC-480, PE conjugate is an antibody against SSEA-1 for use in IH, IP, IF, FC.


Disclaimer


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


General description


SSEA-1 is expressed on the surface of early mouse embryos, murine embryonal carcinoma cells (EC), murine embryonic stem cells (ES) and murine & human germ cells (EG). No immunoreactivity is evident with undifferentiated human EC and ES cells. Expression of SSEA-1 is down regulated following differentiation of murine EC and ES cells. In contrast, the differentiation of human EC and ES cells is characterized by an increase in SSEA-1 expression.


Immunogen


Epitope: MC-480


F9 tetracarcinoma stem cells (X-irradiated).


Other Notes


This antibody reacts with the Stage-specific embryonic antigen-1 (SSEA-1) that is expressed upon the surface of early mouse embryos, murine embryonal carcinoma cells (EC), murine embryonic stem cells (ES) and murine & human germ cells (EG).


Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


Physical form


Ammonium Sulfate Precipitation


Purified mouse monoclonal IgM conjugated to PE fluorochrome in PBS with 0.1% sodium azide and 15 mg/mL BSA.


Quality


Evaluated by Flow Cytometry with mouse embryonic stem cells.


Specificity


This antibody reacts with the Stage-specific embryonic antigen-1 (SSEA-1) that is expressed upon the surface of early mouse embryos, murine embryonal carcinoma cells (EC), murine embryonic stem cells (ES) and murine & human germ cells (EG).


Storage and Stability


Maintain refrigerated at 2-8oC in undiluted aliquots for up to 6 months from date of receipt. Protect from light.


Target description


220 kDa Calculated

ManufacturerSIGMA-ALDRICH

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