P-Selectin; Human; Recombinant; CHO Cells

Stock Code: 3571282
Manufacturer Part No: 561306-50UG
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Biochem/physiol Actions


Shown to bind to P-selectin ligands on U937 cells.


General description


Recombinant, human P-selectin consisting of 730 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is expressed on activated platelets and endothelial cells. A specific interaction between P-selectin and P-selectin glycoprotein ligand-1, present on numerous cell types, promotes adhesion and acts along with L-selectin in establishing an initial interaction between circulating leukocytes and the endothelium.


Legal Information


CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Packaging


50 µg in Plastic ampoule


Physical form


Lyophilized from Dulbecco's D-PBS (containing calcium and magnesium), 1% sorbitol.


Reconstitution


Reconstitute at 1 mg/ml in sterile H2O.


Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.


Warning


Toxicity: Standard Handling (A)

Quality Level100
ManufacturerSIGMA-ALDRICH
Impurities﹤1.5 EU/µg Endotoxins (EU/µg of P-Selectin)
Formlyophilized
Assay≥95% (SDS-PAGE)

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