KGF/FGF-7; Mouse; Recombinant

Stock Code: 3571251
Manufacturer Part No: 422426-25UG
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£535.00 (exc VAT) per 25UG
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Biochem/physiol Actions


ED50 = 10-50 ng/ml as measured in a cell proliferation assay using 4MBr-5 monkey epithelial cells.


General description


Recombinant, mouse keratinocyte growth factor (KGF) consisting of amino acids 32-194 and expressed in E. coli. KGF plays an essential role in development, tumorigenesis, angiogenesis, morphogenesis, and wound healing. Mature mouse KGF amino acid sequence is 96% identical with rat, bovine, ovine, equine, and human forms and is active across species.


Legal Information


CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Other Notes


Belleudi, F., et al. 2007. Traffic8, 1854.Finch, P.W. and J.S. Rubin. 2006. J. Natl. Cancer Inst.98, 812.de Georgi, V., et al. 2007. Dermatol. Clin.25, 477.Niu, J., et al. 2007. J. Biol. Chem.282, 6001.Werner, S., et al. 2007. J. Invest. Dermatol.127, 998.Cardinali, G., et al. 2005. J. Invest. Dermatol.125, 1190.Geer, D.J., et al. 2005. Am. J. Pathol.167, 1575.Hsu, YR., et al. 1999. Biochemistry38, 2523.Qiao, J., et al. 1999. Development126, 547.Werner, S., 1998. Cytokine Growth Factor Rev.9, 153.Guo, L., et al. 1996. Genes Dev.10, 165.Mason, I.J., et al. 1994. Mech. Dev.45, 15.


Packaging


25 µg in Glass bottle


Physical form


Lyophilized from 0.2 µm sterile-filtered MOPS, Na2SO4, EDTA, DTT BSA.


Reconstitution


Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.


Reconstitute to 250 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.


Warning


Toxicity: Standard Handling (A)

Quality Level100
Pack25UG
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Impurities﹤1.0 EU/µg protein Endotoxin
Formsolid
Assay≥90% (SDS-PAGE)

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