Corning BioCoat Collagen IV 100mm TC-Treated Culture Dish, 58.1cm2 Cell Groowth Area

Stock Code: 1638241
Manufacturer Part No: 354453

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Descriptions

Type IV Collagen is a ubiquitous component in basement membranes and provides the major structural support for this matrix. When the Collagen IV meshwork is assembled, it provides a scaffold for the assembly of other basement membrane components through interactions with laminin, entactin/nidogen, and heparan sulfate proteoglycan. Collagen IV is useful as a substrate for growth of epithelial, endothelial, muscle, and nerve cells. Collagen plays a role in the regulation of cell growth, differentiation and adhesion, as well as tissue formation. Applications include promotion of cell attachment and spreading, cell differentiation and neurite outgrowth, increased proliferation of PC12 cells, studies of effects of collagen IV on cell behavior, and cell adhesion assays.

Source: Engelbreth-Holm-Swarm (EHS) lathrytic mouse tumor
Quality control: tested for ability to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cells
Tested and found negative for bacteria and fungi
Collagen IV purity >90% by SDS-PAGE
Storage: 2°C to 8°C, do not freeze