6-Aminocaproic acid, >=99% (titration), powder

6-Aminocaproic acid, >=99% (titration), powder

Stock Code: 3577601
Manufacturer Part No: A2504-25G
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£65.60 (exc VAT) per 25G
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Application


EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.


Biochem/physiol Actions


Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.


EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carbo­xy­peptidase, plasmin, and plasminogen activator.


Packaging


5 kg in poly drum


25, 100, 500 g in poly bottle


1 kg in poly bottle

Colourwhite
mp207-209 °C (dec.) (lit.)
InChI keySLXKOJJOQWFEFD-UHFFFAOYSA-N
InChI1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥99% (titration)

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