51164

51164

Stock Code: 3576570
Manufacturer Part No: SML2605-5MG
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Biochem/physiol Actions


51164 is a neuron penetrant, potent and selective positive allosteric modulator of TRPC6 channels that activates neuronal store-operated calcium entry (nSOCE) in the hippocampal neurons spines. 51164 fully rescues mushroom spines in Aß42-treated neurons. It restores long-term potentiation (LTP) deficit in 6 months old hippocampal slices from 5xFAD mouse model.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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