5-Fluoroorotic acid hydrate, >=98%

Stock Code: 3578279
Manufacturer Part No: F5013-1G
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£971.25 (exc VAT) per 1G
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Application


5-Fluoroorotic acid hydrate has also been used as a counter-selection agent to screen L. lactis (multi) peptidase knockout mutants and C. albicans. It has been used in synthesis of 5-fluoroorotidine 5?-monophosphate (FOMP).


Useful in the selection of orotidine-5′-phosphate decarboxylase mutants of Saccharomyces cerevisiae.


Biochem/physiol Actions


5-Fluoroorotic acid is a selective inhibitor of rRNA synthesis in mammals.


Packaging


1 g in poly bottle


50 mg in glass insert


250 mg in poly bottle

Quality Level200
mp278 °C (dec.) (lit.)
InChI keyLODRRYMGPWQCTR-UHFFFAOYSA-N
InChI1S/C5H3FN2O4.H2O/c6-1-2(4(10)11)7-5(12)8-3(1)9;/h(H,10,11)(H2,7,8,9,12);1H2
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98%

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