1S;3R-RSL 3

Stock Code: 3576007
Manufacturer Part No: SML2234-25MG
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£565.50 (exc VAT) per 25MG
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Application


1S,3R-RSL 3 has been used:as a glutathione peroxidase 4 (GPX4) inhibitor to study its effects on cell death in subventricular glioblastoma multiforme (GBM) linesGPX4 inhibitor and ferroptosis inducer to study its effects on cardiomyocyte death and heart failure in miceas a ferroptosis inducer in HT-1080 cellsin cell viability assay


Biochem/physiol Actions


RSL3 is an inducer of ferroptosis. It acts by a different method than erastin to induce ferroptosis by inhibiting glutathione peroxidase 4 (GPX4).

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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