1-EBIO, >=98% (HPLC)

1-EBIO, >=98% (HPLC)

Stock Code: 3573991
Manufacturer Part No: SML0034-10MG
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£118.67 (exc VAT) per 10MG
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Application


1-EBIO was used to study the electrical activity modulated by Ca+2-activated K+ channels in rat central neurons. The effect of 1-EBIO on human intermediate conductance channels was studied.


Biochem/physiol Actions


1-EBIO potentiates the secretion of CFTR-mediated Cl? ion secretion by activating the basolateral KCNN4 K+ channels in native human colonic tissues. It stimulates the apical Cl? channels and Ca+2-dependent basolateral K+ channels to stimulate fluid transport in lacrimal glands.


1-EBIO is an activator of epithelial Ca2+-activated K+ channel also known as the intermediate-conductance Ca(2+)-activated K(+) channel (IK-1) or KCa3.1.


Packaging


10, 50 mg in glass bottle

Quality Level100
InChI keyCXUCKELNYMZTRT-UHFFFAOYSA-N
InChI1S/C9H10N2O/c1-2-11-8-6-4-3-5-7(8)10-9(11)12/h3-6H,2H2,1H3,(H,10,12)
ManufacturerSIGMA-ALDRICH
Storage Temp.room temp
SolubilityDMSO: ≥20 mg/mL
Formpowder
Assay≥98% (HPLC)

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