(Tyr[SO3H]27)Cholecystokinin fragment 26-33 Amide, >=97% (HPLC), powder

Stock Code: 3589813
Manufacturer Part No: C2175-.5MG

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Descriptions

Amino Acid Sequence

Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2

Application

(Tyr[SO₃H]²⁷)Cholecystokinin fragment 26-33 amide has been used to test its effects:to study its effects on ?5i/LMP7 immunoproteasome subunit in pancreatitison gastric emptying,food intake and c-Fos immunoreactivity in small litter (SL) and normal litter (NL) ratson the intestine and gallbladder motility in fish Ballan Wrasse

Biochem/physiol Actions

(Tyr[SO₃H]²⁷)Cholecystokinin fragment 26-33 amide activates the cholecystokinin type B receptor and may mediate the blockage of opioid analgesia. It elicits anti-inflammatory effects. It mediates the inhibition on cytokine release, lymphocytes, and macrophages.

Neurotransmitter; predominant form of CCK in CNS and gastrointestinal tract; may play a role in satiety.

General description

(Tyr[SO₃H]²⁷)Cholecystokinin fragment 26-33 amide is a sulfated cholecystokinin(CCK) octapeptide derived from the proCCK. It is present in plasma and endocrine cells.

Other Notes

C-Terminal octapeptide of cholecystokinin

Specifications

Quality Level	200
InChI key	IZTQOLKUZKXIRV-IVVJSLGPSA-N
InChI	1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10
Manufacturer	SIGMA-ALDRICH
Storage Temp.	−20°C
Form	powder
Assay	≥97% (HPLC)