MONOCLONAL PAX-5 (24)

MONOCLONAL PAX-5 (24)

Stock Code: 3572973
Manufacturer Part No: 312M-15
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General description


PAX-5 encodes for B-cell-specific activator protein (BSAP), a marker for B-cells, including B-lymphoblastic neoplasms and maturation stage. It is found in most cases of mature and precursor B-cell non-Hodgkin lymphomas/leukemias. In approximately 97% of cases of classic Hodgkin lymphoma, Reed-Sternberg cells express PAX-5. PAX-5 is not detected in multiple myeloma and solitary plasmacytoma, making it useful for such differentiation. Diffuse large B-cell lymphomas do express PAX-5, save for those with terminal B-cell differentiation. T-cell neoplasms do not stain with anti-PAX-5. There is a strong association with CD20 expression.


Legal Information


Cell Marque is a trademark of Sigma-Aldrich Co. LLC


Linkage


PAX-5 Positive Control Slides, Product No. 312S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).


Other Notes


For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com


Physical form


Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide


Preparation Note


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Quality


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Quality Level100; 500
ManufacturerSIGMA-ALDRICH
Further InfoFor In Vitro Diagnostic Use in Select Regions (See Chart)
Storage Temp.2-8°C
Formbuffered aqueous solution

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