ZOTAROLIMUS

ZOTAROLIMUS

Biochem/physiol Actions

Zotarolimus (ABT-578) is a semi-synthetic rapamycin analog with immunosuppressant and anti-proliferative activity. It binds to the FKBP12 binding protein, which subsequently binds to the mammalian target of rapamycin (mTOR) causing cell cycle arrest in the G1 phase. Zotarolimus was designed to be used for delivery from drug-eluting coronary stents to prevent restenosis.

Zotarolimus is a second generation Drug Eluting Stent (DES).

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575944 ZOTAROLIMUS white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£357.96 (exc VAT) per 25MG
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3575945 ZOTAROLIMUS white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£111.15 (exc VAT) per 5MG
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