Y16

Y16

Biochem/physiol Actions

Y16 blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM). Y16 specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways. Y16 blocks the growth and migration of MCF7 breast cancer cells.

Features and Benefits

This compound is featured on the GTP Binding Proteins (Low Molecular Weight) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Other Notes

Product is a racemic mixture of E/Z isomers.

Packaging

5, 25 mg in glass bottle

No detailed specifications are available for this product.

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574189 Y16 , faint yellow to dark orange 100 SIGMA-ALDRICH 2-8°C
£123.83 (exc VAT) per 25MG
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3574190 Y16 , faint yellow to dark orange 100 SIGMA-ALDRICH 2-8°C
£120.06 (exc VAT) per 5MG
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