Vancomycin hydrochloride from Streptomyces orientalis has been used as: an antibiotic in screening: minimal inhibitory concentrations (MICs) Streptomyces coelicolorin treating Leishmania infected sand fliesin combined antibiotic treatment in asthma induced mice
Biochem/physiol Actions
Glycopeptide antibioticMode of action: Used to block bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis by inhibiting incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides.Antimicrobial spectrum: Gram-positive bacteria
Vancomycin is used for treating methicillin-resistantStaphylococcus aureus(MRSA) infections and shunt-associated Staphylococcal ventriculitis. It may lead to hypersensitivity reactions like anaphylaxis and red man syndrome. Vanomycin is also used to treat thrombocytopenia and induces drug reaction with eosinophilia and systemic symptoms (DRESS) on usage.
General description
Vancomycin is a heptapeptide.
Chemical structure: glycopeptide
Other Notes
Keep container tightly closed in a dry and well-ventilated place.