ULIPRISTAL ACETATE

ULIPRISTAL ACETATE

Biochem/physiol Actions

Ulipristal acetate is a selective progesterone receptor modulator (SPRM) with tissue-selective partial antagonist activity. It has clinical use both as an emergency contraceptive and as a treatment for uterine fibroids. Ulipristal acetate acts as a partial antagonist on the hypothalamic–pituitary–ovarian axis to inhibit or delay ovulation without affecting human embryo implantation. As a progesterone antagonist, Ulipristal acetate selectively suppresses neo-vascularization, cell proliferation, and survival in uterine fibroid cells, but not in normal myometrial cells.

Ulipristal acetate is known to reduce uncontrolled bleeding due to post uterine fibroid surgery.

Packaging

10, 50 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3574954 ULIPRISTAL ACETATE white to beige 100 OOLLAFOLCSJHRE-ZHAKMVSLSA-N 1S/C30H37NO4/c1-18(32)30(35-19(2)33)15-14-27-25-12-8-21-16-23(34)11-13-24(21)28(25)26(17-29(27,30)3)20-6-9-22(10-7-20)31(4)5/h6-7,9-10,16,25-27H,8,11-15,17H2,1 SIGMA-ALDRICH powder ≥98% (HPLC)
£128.28 (exc VAT) per 10MG
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3574955 ULIPRISTAL ACETATE white to beige 100 OOLLAFOLCSJHRE-ZHAKMVSLSA-N 1S/C30H37NO4/c1-18(32)30(35-19(2)33)15-14-27-25-12-8-21-16-23(34)11-13-24(21)28(25)26(17-29(27,30)3)20-6-9-22(10-7-20)31(4)5/h6-7,9-10,16,25-27H,8,11-15,17H2,1 SIGMA-ALDRICH powder ≥98% (HPLC)
£518.14 (exc VAT) per 50MG
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