TP-238 HYDROCHLORIDE

TP-238 HYDROCHLORIDE

Biochem/physiol Actions

TP-238 is a chemical probe for CECR2 (cat eye syndrome chromosome region, candidate 2), a gene expressed in the nervous system involved in neurulation, and for BPTF bromodomains. It has an activity of 10-30 nM with CECR2 and 100-350 nM with BPTF. TP-238 showed an IC50 of 30nM against CECR2 and 350nM against BPTF in an alphascreen assay and a KD of 10nM for CECR2 and 120nM for BPTF by ITC. The structurally related negative control TP-422 is completely inactive against BPTF and CECR2.

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576306 TP-238 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH −20°C
£681.11 (exc VAT) per EACH
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3576307 TP-238 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH −20°C
£171.32 (exc VAT) per EACH
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