Tigecycline hydrate, >=98% (HPLC)

Tigecycline hydrate, >=98% (HPLC)

Application

TIGECYCLINE HYDRATE has been used:for antibiotic susceptibility testingto study its effects on multiple nonsmall cell lung cancer (NSCLC) cell linesto evaluate its effects on the binding of fluoroquinolones to human serum albuminas a standard to investigate the penetration of tigecycline into cornea, aqueous humor and vitreous humor

Biochem/physiol Actions

Tigecycline is a broad spectrum glycylcycline antibiotic. Tigecycline is bacteriostatic, that inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline is active against resistant strains of gram-positive and gram-negative bacteria, avoiding the two most common mechanisms of resistance to the tetracycline antimicrobials: tetracycline efflux pump proteins and ribosomal protection proteins.

General description

Tigecycline is used to treat complicated skin and skin structure infections (cSSSI) and complicated intraabdominal infections.

Legal Information

Pfizer is a registered trademark of Pfizer, Inc.

Sold for research purposes under agreement from Pfizer Inc.

Other Notes

This compound was developed by Pfizer for Immunology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

air sensitive

Packaging

5, 25 mg in glass bottle

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Code Description Colour InChI key InChI Manufacturer Form Assay Price Quantity
3573551 Tigecycline hydrate, >=98% (HPLC) off-white to yellow-brown PMPLAEFBZIFHAR-KXLOKULZSA-N 1S/C29H39N5O8.H2O/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36;/h10,12,14, SIGMA-ALDRICH
£674.14 (exc VAT) per 25MG
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3573552 Tigecycline hydrate, >=98% (HPLC) off-white to yellow-brown PMPLAEFBZIFHAR-KXLOKULZSA-N 1S/C29H39N5O8.H2O/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36;/h10,12,14, SIGMA-ALDRICH
£179.68 (exc VAT) per 5MG
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