Thyroglobulin from porcine thyroid gland, powder

Biochem/physiol Actions

Thyroglobulin is a major protein involved with iodine metabolism. It consists of an iodine-containing protein that is stored in the thyroid gland and is converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary. Thyroglobulin is often used as a carrier protein for the production of antibodies. Its advantage as a carrier protein comes from its large number of tyrosine residues that can be used for conjugation using the diazo reaction.

Thyroglobulin has been shown to regulate the transcription of iodide porters including sodium iodide symporter and pendrin.

Other Notes

Electrophoretically heterogeneous.

Packaging

100, 500 mg in poly bottle

1 g in poly bottle

Preparation Note

When reconstituted in water (20 mg/ml), a turbid solution with some insolubles is observed.

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Code Description Manufacturer Composition Form Price Quantity
3593702 Thyroglobulin from porcine thyroid gland, powder SIGMA-ALDRICH Iodine, ≥0.3% powder
£358.29 (exc VAT) per 100MG
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3593703 Thyroglobulin from porcine thyroid gland, powder SIGMA-ALDRICH Iodine, ≥0.3% powder
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3593704 Thyroglobulin from porcine thyroid gland, powder SIGMA-ALDRICH Iodine, ≥0.3% powder
£823.79 (exc VAT) per 500MG
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