THAL-SNS-032

THAL-SNS-032

Biochem/physiol Actions

THAL-SNS-032 is a selective inhibitor and degrader of cyclin-dependent kinase 9 (CDK9). It links the CDK inhibitor SNS-032 to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon. THAL-SNS-032 was found to selectively induce degradation of CDK9 over other CDKs. It inhibited proliferation across a panel of 11 different leukemia cancer cell lines potently than SNS-032.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576691 THAL-SNS-032 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£135.39 (exc VAT) per EACH
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3576692 THAL-SNS-032 white to beige SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear
£516.75 (exc VAT) per EACH
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