TH5487

TH5487

Biochem/physiol Actions

TH5487 is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1), which is part of the DNA base excision repair pathway. TH5487 as shown to inhibit OGG1-dependent proinflammatory gene expression by binding in the OGG1 active site, preventing OGG1 from engaging damaged DNA in vitro and in cells, resulting in decreased proinflammatory gene expression.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576447 TH5487 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£760.50 (exc VAT) per 25MG
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3576448 TH5487 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear
£196.39 (exc VAT) per 5MG
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