TH1020

TH1020

Application

TH1020 has been used to inhibit toll-like receptor 5 (TLR5) in porcine intestinal epithelial monolayer cells and mice.

Biochem/physiol Actions

TH1020 mediates the inhibition of tumor necrosis factor-? (TNF-?) based signaling, It disrupts tetrameric complex by binding the molecular interface between dimeric TLR5.

TH1020 is a non-cytotoxic non-cytotoxic toll-like receptor 5 (TLR5)/flagellin complex inhibitor. TH1020 selectively prevents flagellin-induced TLR5 signaling without affecting ligands-induced activation of TLR2, TLR3, TLR4, TLR7 or TLR8.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575332 TH1020 white to beige 100 SIGMA-ALDRICH 2-8°C
£536.25 (exc VAT) per 25MG
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3575333 TH1020 white to beige 100 SIGMA-ALDRICH 2-8°C
£131.76 (exc VAT) per 5MG
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