TENOFOVIR

TENOFOVIR

Biochem/physiol Actions

Tenofovir is a nucleotide analogue reverse transcriptase inhibitor (nRTI) that causes premature termination of DNA transcription. Tenofovir is an antiretroviral used for HIV treatment and prevention.

Tenofovir has a low oral bioavailability. Hence, it is available as a prodrug called tenofovir disoproxil fumarate. Once ingested, tenofovir disoproxil fumarate is hydrolyzed to tenofovir and phosphorylated. This is then incorporated into the viral DNA which leads to chain termination. Tenofovir is also effective against hepatitis B virus.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3575392 TENOFOVIR white to beige 100 SGOIRFVFHAKUTI-ZCFIWIBFSA-N 1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1 SIGMA-ALDRICH powder ≥98% (HPLC)
£671.36 (exc VAT) per 25MG
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3575393 TENOFOVIR white to beige 100 SGOIRFVFHAKUTI-ZCFIWIBFSA-N 1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1 SIGMA-ALDRICH powder ≥98% (HPLC)
£208.93 (exc VAT) per 5MG
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