TENATOPRAZOLE

TENATOPRAZOLE

Biochem/physiol Actions

Tenatoprazole is used to maintain high diurnal and nocturnal pH levels. It prevents gastric H+,K+-ATPase with potency similar to omeprazole.

Tenatoprazole is a proton pump inhibitor. Tenatoprazole is an acid-activated prodrug that binds covalently to gastric H,K-ATPase, resulting in acid secretion inhibition. Tenatoprazole has a different structural class from omeprazole and most other proton pump inhibitors, with an imidazopyridine backbone rather than benzimidazole, which results in slower metabolism. Tenatoprazole thus has a long plasma half-life as compared to omeprazole, resulting in prolonged inhibition of acid secretion.

General description

Tenatoprazole is a novel proton pump inhibitor with an imidazopyridine backbone. It has seven-fold longer plasma half-life. It is also called as 5-methoxy-2-(4-methoxy-3,5-dimethyl-pyridin-2-ylmethanesulfinyl)-1H-imidazo[4,5-b]pyridine.Tenatoprazole is a member of the class of covalent proton pump inhibitors.

Packaging

10, 50 mg in glass bottle

No detailed specifications are available for this product.

There are no downloads for this product.

Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3574910 TENATOPRAZOLE white to beige 100 ZBFDAUIVDSSISP-UHFFFAOYSA-N 1S/C16H18N4O3S/c1-9-7-17-12(10(2)14(9)23-4)8-24(21)16-18-11-5-6-13(22-3)19-15(11)20-16/h5-7H,8H2,1-4H3,(H,18,19,20) SIGMA-ALDRICH DMSO: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
£90.68 (exc VAT) per 10MG
-
+
3574911 TENATOPRAZOLE white to beige 100 ZBFDAUIVDSSISP-UHFFFAOYSA-N 1S/C16H18N4O3S/c1-9-7-17-12(10(2)14(9)23-4)8-24(21)16-18-11-5-6-13(22-3)19-15(11)20-16/h5-7H,8H2,1-4H3,(H,18,19,20) SIGMA-ALDRICH DMSO: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
£268.82 (exc VAT) per 50MG
-
+