TCN-201, >=98% (HPLC)

TCN-201, >=98% (HPLC)

Biochem/physiol Actions

TCN-201 is the first NMDA receptor antagonist that is specific for NR2A-subunit containing receptors. The pIC50 for NR2A NMDA receptors is 6.8. TCN-201has no effect on NR2B-containing receptors at concentrations up to 50 mM.

TCN-201 is a sulphonamide derivative, that negatively modulates glycine binding to the GluN1 (glutamate receptor subunit) subunit of the receptor.

Features and Benefits

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3574072 TCN-201, >=98% (HPLC) white to beige 100 FYIBXBFDXNPBSF-UHFFFAOYSA-N 1S/C21H17ClFN3O4S/c22-18-12-17(10-11-19(18)23)31(29,30)24-13-14-6-8-16(9-7-14)21(28)26-25-20(27)15-4-2-1-3-5-15/h1-12,24H,13H2,(H,25,27)(H,26,28) SIGMA-ALDRICH DMSO: 5 mg/mL (clear solution) powder ≥98% (HPLC)
£463.82 (exc VAT) per 25MG
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3574073 TCN-201, >=98% (HPLC) white to beige 100 FYIBXBFDXNPBSF-UHFFFAOYSA-N 1S/C21H17ClFN3O4S/c22-18-12-17(10-11-19(18)23)31(29,30)24-13-14-6-8-16(9-7-14)21(28)26-25-20(27)15-4-2-1-3-5-15/h1-12,24H,13H2,(H,25,27)(H,26,28) SIGMA-ALDRICH DMSO: 5 mg/mL (clear solution) powder ≥98% (HPLC)
£143.46 (exc VAT) per 5MG
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