Tat-Beclin 1,

Tat-Beclin 1,

Biochem/physiol Actions

The TAT-BECLIN-1 (autophagy activator) peptide reduces the accumulation of polyglutamine aggregates and pathogen replication in vitro. This peptide is also found to reduce the mortality of mice infected by different viruses. The TAT-BECLIN-1 peptide is predicted to stimulate cell death via autophagy.

General description

The TAT-BECLIN-1 (autophagy activator) peptide is derived from a region of the autophagy protein, beclin 1, attached to the HIV-1 Tat protein transduction domain. The peptide includes 11 amino acids at the N terminus derived from the Tat protein transduction domain, 18 amino acids (267–284 aa) from beclin 1 at the C terminus and a GG linker.

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Code Description Quality Level Manufacturer Storage Temp. Form Assay Price Quantity
3593707 Tat-Beclin 1, 200 SIGMA-ALDRICH −20°C lyophilized powder ≥95% (HPLC)
£457.65 (exc VAT) per 100UG
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3593708 Tat-Beclin 1, 200 SIGMA-ALDRICH −20°C lyophilized powder ≥95% (HPLC)
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