TAROCIN A1

TAROCIN A1

Biochem/physiol Actions

Tarocin A1 is an oxazolidinone which inhibits TarO, the first enzyme in teichoic acid synthesis. Tarocin A1 has an IC50 value of 40 nM in a biochemical TarO assay. Tarocin A does not inhibit bacterial growth alone, and exhibits no cytotoxicity against HeLa cells, but it has potent bactericidal syergism with broad spectrum β-lactams, and may restore the clinical efficacy of existing β-lactam antibiotics.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3575252 TAROCIN A1 white to beige 100 XWMRKUPNQVITEC-ZSEKCTLFSA-N 1S/C24H18F6N2O3/c1-13-21(16-8-17(23(25,26)27)10-18(9-16)24(28,29)30)35-22(34)32(13)20(33)7-6-15-12-31-11-14-4-2-3-5-19(14)15/h2-5,8-13,21H,6-7H2,1H3/t13-,21-/m SIGMA-ALDRICH DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
£502.82 (exc VAT) per 25MG
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3575253 TAROCIN A1 white to beige 100 XWMRKUPNQVITEC-ZSEKCTLFSA-N 1S/C24H18F6N2O3/c1-13-21(16-8-17(23(25,26)27)10-18(9-16)24(28,29)30)35-22(34)32(13)20(33)7-6-15-12-31-11-14-4-2-3-5-19(14)15/h2-5,8-13,21H,6-7H2,1H3/t13-,21-/m SIGMA-ALDRICH DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
£140.68 (exc VAT) per 5MG
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