SW033291

SW033291

Biochem/physiol Actions

SW033291 is an inhibitor of the prostaglandin-degrading enzyme 15-PGDH. PGE2 is known to promote hematopoiesis and to promote reeneration by causing stem cells to proliferate. 15-PGDH degrades prostaglandin PGE2 and is a negative regulator of tissue regeneration and repair. SW033291 inhibition of 15-PGDH doubled levels of PGE2 and doubled rates of colon and liver tissue regeneration. Mice given SW033291 after receiving a bone marrow transplant had a two- to threefold increase in the number of donor cells that homed to the their bone marrow.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3574973 SW033291 light yellow to yellow-green 100 LCYAYKSMOVLVRL-UHFFFAOYSA-N 1S/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11,13H,2-3,12,22H2,1H3
£632.36 (exc VAT) per 25MG
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3574974 SW033291 light yellow to yellow-green 100 LCYAYKSMOVLVRL-UHFFFAOYSA-N 1S/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11,13H,2-3,12,22H2,1H3
£235.39 (exc VAT) per 5MG
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