Substance P acetate salt hydrate, >=95% (HPLC), powder

Substance P acetate salt hydrate, >=95% (HPLC), powder

Amino Acid Sequence

Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2

Application

Substance P acetate salt hydrate has been:used as a neurokinin 1 (NK1) receptor agonist for the activation of spinal nociceptive circuitry in miceadministered in central nucleus (ACE) in rat to study its positive reinforcing effectsused as an inhibitor of myosin light chain kinase in isolated lymphatic vessels from rat

Substance P acetate salt hydrate has been used in competition binding assays.

Biochem/physiol Actions

NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; increases capillary permeability; induces mast cell degranulation; putative neurotransmitter in sensory (pain) afferents.

Substance P has proinflammatory effects on epithelial and immune cells. It has been associated with inflammatory diseases related to gastrointestinal and respiratory systems. Substance P modulates contractility of smooth muscles, transport of ions in the epithelium, vascular permeability and immune functions in the gut.

General description

Substance P is a small peptide produced by macrophages, lymphocytes, eosinophils, dendritic cells and nerves. It is part of the neurokinin group.

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Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price Quantity
3592212 Substance P acetate salt hydrate, >=95% (HPLC), powder white 200 VHKFRLDSEZYWAC-CIYRQLMPSA-N 1S/C63H98N18O13S.C2H4O2.H2O/c1-37(2)33-45(57(89)74-41(53(68)85)27-32-95-3)73-52(84)36-72-54(86)46(34-38-15-6-4-7-16-38)78-58(90)47(35-39-17-8-5-9-18-39)79-56(8
£77.72 (exc VAT) per EACH
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3592213 Substance P acetate salt hydrate, >=95% (HPLC), powder white 200 VHKFRLDSEZYWAC-CIYRQLMPSA-N 1S/C63H98N18O13S.C2H4O2.H2O/c1-37(2)33-45(57(89)74-41(53(68)85)27-32-95-3)73-52(84)36-72-54(86)46(34-38-15-6-4-7-16-38)78-58(90)47(35-39-17-8-5-9-18-39)79-56(8
£739.61 (exc VAT) per 10MG
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3592214 Substance P acetate salt hydrate, >=95% (HPLC), powder white 200 VHKFRLDSEZYWAC-CIYRQLMPSA-N 1S/C63H98N18O13S.C2H4O2.H2O/c1-37(2)33-45(57(89)74-41(53(68)85)27-32-95-3)73-52(84)36-72-54(86)46(34-38-15-6-4-7-16-38)78-58(90)47(35-39-17-8-5-9-18-39)79-56(8
£112.82 (exc VAT) per 1MG
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3592215 Substance P acetate salt hydrate, >=95% (HPLC), powder white 200 VHKFRLDSEZYWAC-CIYRQLMPSA-N 1S/C63H98N18O13S.C2H4O2.H2O/c1-37(2)33-45(57(89)74-41(53(68)85)27-32-95-3)73-52(84)36-72-54(86)46(34-38-15-6-4-7-16-38)78-58(90)47(35-39-17-8-5-9-18-39)79-56(8
£1,085.04 (exc VAT) per 25MG
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3592216 Substance P acetate salt hydrate, >=95% (HPLC), powder white 200 VHKFRLDSEZYWAC-CIYRQLMPSA-N 1S/C63H98N18O13S.C2H4O2.H2O/c1-37(2)33-45(57(89)74-41(53(68)85)27-32-95-3)73-52(84)36-72-54(86)46(34-38-15-6-4-7-16-38)78-58(90)47(35-39-17-8-5-9-18-39)79-56(8
£427.61 (exc VAT) per 5MG
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